I am not sure whether or not someone has done this before me, nor do I really care. I would just like to share this method with you.
Basically, combine the Thurisaz rune with your standard curse method. I found that Thurisaz + spirit = fast, sudden death or injury.
Runes work very well with spirits. You can also use this for money magic. Fehu + Lucifuge, or Mammon = fast $$$$$
If you want your target obliterated just combine the Thurisaz rune with Abaddon, for example, and enjoy the carnage.
That is all.